Search results for " system b"

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

2018

International audience; C-reactive protein (CRP) is a sensitive biomarker of chronic low-grade inflammation and is associated with multiple complex diseases. The genetic determinants of chronic inflammation remain largely unknown, and the causal role of CRP in several clinical outcomes is debated. We performed two genome-wide association studies (GWASs), on HapMap and 1000 Genomes imputed data, of circulating amounts of CRP by using data from 88 studies comprising 204,402 European individuals. Additionally, we performed in silico functional analyses and Mendelian randomization analyses with several clinical outcomes. The GWAS meta-analyses of CRP revealed 58 distinct genetic loci (p < 5 × 1…

BioMet14 XIV PharmacoBioMetallics Pisa, 24-25 ottobre 2014

2014

Lymphocyte apoptosis in children with central nervous system tuberculosis: a case control study

2011

Abstract Background Studies of the apoptosis mechanisms involved in the pathogenesis of tuberculosis have suggested that Mycobacterium tuberculosis can actively interfere with the apoptosis of infected cells. In vivo studies have been performed in adult populations but have not focused on this process in children. In the present study, we analyzed spontaneous T lymphocyte (PBT) apoptosis in the peripheral blood of children with central nervous system tuberculosis (CNS TB), before and after chemotherapy, and compared the results with healthy controls. Methods A case-control study was conducted from January 2002 to June 2009. It included 18 children with CNS TB and 17 healthy controls. Sponta…

A Knowledge Based Decision Support System for Bioinformatics and System Biology

2011

In this paper, we present a new Decision Support System for Bioinformatics and System Biology issues. Our system is based on a Knowledge base, representing the expertise about the application domain, and a Reasoner. The Reasoner, consulting the Knowledge base and according to the user’s request, is able to suggest one or more strategies in order to resolve the selected problem. Moreover, the system can build, at different abstraction layers, a workflow for the current problem on the basis of the user’s choices, freeing the user from implementation details and assisting him in the correct configuration of the algorithms. Two possible application scenarios will be introduced: the analysis of …

ON THE “SOLAR SYSTEM SMALL BODIES” ASTROPLATE PROJECT OF THE UKRAINIAN VIRTUAL OBSERVATORY

2019

The UkrVO Joint Digital Archive of astro- plates and the newest digitized data processing services al- lowed us to form a new approach for the creation of catalogs of astrometric and photometric characteristics of the Solar System bodies. Given this, the main goal of this approach was not only to complete the processing with the best possi- ble accuracy of high-quality and unprocessed earlier photo- graphic observations of the Solar System bodies but also to find new original data from these observations. As a result, more than 6,500 new astrometric positions and stellar magnitudes of asteroids, and 3,036 positions of outer planets (Pluto, Uranus, Neptune, Saturn, Jupiter) and their satelli…

INFLUENZA DI DIFFERENTI SPESSORI DENTINALI SULLA PROPAGAZIONE DEL CALORE LUNGO LA SUPERFICIE RADICOLARE

2009

Incremento termico sulla superficie radicolare durante l'uso del System B

2008

Termografia computerizzata a infrarossi delle temperature generate usando il System B lungo la superficie radicolare

2009

Small solar system bodies as granular systems

2017

Asteroids and other Small Solar System Bodies (SSSBs) are currently of great scientific and even industrial interest. Asteroids exist as the permanent record of the formation of the Solar System and therefore hold many clues to its understanding as a whole, as well as insights into the formation of planetary bodies. Additionally, SSSBs are being investigated in the context of impact risks for the Earth, space situational awareness and their possible industrial exploitation (asteroid mining). In all these aspects, the knowledge of the geophysical characteristics of SSSB surface and internal structure are of great importance. Given their size, constitution, and the evidence that many SSSBs ar…

Transformation of the European security system in the context of current geopolitical challenges

2017

W artykule rozważa się problem modernizacji europejskiego systemu bezpieczeństwa w kontekście współczesnych wyzwań geopolitycznych, zwłaszcza agresywnej polityki Federacji Rosyjskiej. Przeprowadzono analizę kształtowania systemu europejskiego bezpieczeństwa, biorąc pod uwagę wielowymiarowość i zdolność systemu, wyznaczono czynniki zagrożenia i wyzwania, które decydują obecnie o jego funkcjonowaniu. Autorzy zwracają uwagę na nieefektywność europejskiego systemu bezpieczeństwa, jego problemy i możliwe sposoby jego reformowania. Przeanalizowane główne instytucje europejskiego systemu bezpieczeństwa: NATO (szczególny wkład tej struktury w gwarantowanie pokoju i bezpieczeństwa na kontynencie eur…